RESEARCH ARTICLE


Beneficial Effects of Herbal Medicine on Susceptibility to Infection in a Patient with Immunoglobulin Deficiency



Zenichiro Kato*, Takahide Teramoto, Naomi Kondo
Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu 501- 1194, Japan.


© 2009 Kato et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu 501- 1194, Japan; Tel: +81-58-230-6386; Fax: +81-58-230-6387; E-mail: zenkato@mac.com


Abstract

A case of immunoglobulin deficiency suffered from recurrent enterocolitis and otitis media was treated by Shoukenchuto, one of the Japanese herbal medicines (Kampo), and his susceptibility to infection markedly improved. The increase in the T cell percentage and in the lymphocyte proliferation in our patient suggests the importance of regulatory function of T cells for clinical improvement. The findings in our case and the previously reported cases suggest the usefulness of Japanese herbal medicine or Chinese medicine as an alternative or a supportive therapy for patients with immunological abnormalities.

Keywords: Herbal medicine, Shoukenchuto, immunoglobulin deficiency, CD4, CD8, lymphocyte proliferation.